A 78-year-old woman comes to the clinic for a new-patient examination. She reports that she smokes Cannabis several times a week and also takes alprazolam 0.5 mg three times per day, a combination tablet of metoprolol tartrate 50 mg/hydrochlorothiazide 25 mg daily, aspirin 81 mg daily; garlic soft-gels 1000 mg twice a day; and ibuprofen 400 mg four times a day.
1. Do any of these drugs appear on the 2015 American Geriatrics Society Beers Criteria for Potentially Inappropriate Medication Use in Older Adults? If so, what do the criteria say about them?
2. What interactions exist among the drugs
and supplements this patient is taking?
3. What is the evidence for taking garlic to reduce cholesterol?