Anemias Case Study
A 5 year old son of a Liberian exchange student was hospitalized because of severe diarrhea, abdominal distention and splenomegaly. On admission the following tests were ordered: CBC, bilirubin, hemoglobin electrophoresis, electrolyte studies, urinalysis and stool culture. The results of these tests were as follows:
RBC: 2.06 x 106/ul
Hb: 5.8 g/dl
MCV: 96.4 fl
MCHC: 32 g/dl
The peripheral blood smear revealed moderate aniso, 4 + poik, 3+ poly, occasional HJ bodies, 2+ drepanocytes, and 2 + codocytes and 12 NRBCs. The patient’s total bilirubin was 6.0 mg/dl. The patient had severely abnormal electrolyte levels.
- What is the cause of this patient’s condition?
- What is the clinical course of this disease?
- Explain the presence of the drepanocytes and NRBCs on the peripheral blood smear.
- What additional tests should be ordered to confirm your diagnosis?
5. What kind of treatment should this patient receive?